Early Alzheimer-type lesions in cognitively normal subjects
نویسندگان
چکیده
منابع مشابه
Reliability and reproducibility of perfusion MRI in cognitively normal subjects.
Arterial spin labeling (ASL) magnetic resonance imaging (MRI) is becoming a popular method for measuring perfusion due to its ability of generating perfusion maps noninvasively. This allows for frequent repeat scanning, which is especially useful for follow-up studies. However, limited information is available regarding the reliability and reproducibility of ASL perfusion measurements. Here, th...
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BACKGROUND Structural magnetic resonance imaging is used to longitudinally monitor the progression of Alzheimer disease from its presymptomatic to symptomatic phases. Using magnetic resonance imaging data from the Alzheimer's Disease Neuroimaging Initiative, we tested the hypothesis that surgery would impact brain parameters associated with progression of dementia. METHODS Brain images from t...
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Objective: The aim of the present article was to study the relationship between early maladaptive schemas and the defense styles (mature, immature, and neurotic) in asthmatics, alexithymics and normal subjects. Methods: 216 asthmatic, alexithymic and normal subjects were selected and they completed Young Schema Questionnaire (short form), Defense Style Questionnaire and the Farsi version of ...
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IMPORTANCE Criteria for preclinical Alzheimer disease (AD) propose β-amyloid (Aβ) plaques to initiate neurodegeneration within AD-affected regions. However, some cognitively normal older individuals harbor neural injury similar to patients with AD, without concurrent Aβ burden. Such findings challenge the proposed sequence and suggest that Aβ-independent precursors underlie AD-typical neurodege...
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ژورنال
عنوان ژورنال: Neurobiology of Aging
سال: 2018
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2017.10.002